Caffeine can make you crash hard: Research


WEB DESK: Do you think that caffeine is really important to kick start your day? Or you think its drug that can boost you and activate you for all the day?? Well it’s just a sneaky imposer.

Caffeine may give you that much-needed morning boost, but it can also make you crash—hard. It takes about four cups of coffee to block half of the brain’s A1 receptors. With that many receptors clogged, the adenosine mounting in your body has nowhere to go.

When the caffeine wears off, all that extra adenosine rushes through your receptors. It takes a long time for your body to process the huge flow of new metabolites. And guess what? It leaves you feeling even groggier than you felt before.

Let’s talk about this process which happens inside the brain when you have caffeine.

A neuro-chemical called adenosine builds up in your body as your neurons blaze throughout the day. The nervous system uses special receptors to monitor your body’s adenosine levels. As the day wears on, more and more adenosine passes through those receptors—and it makes you sleepy. It’s one of the reasons you get tired at night.

Caffeine, however, is a stealthy impersonator. It’s the same size and shape as adenosine, and when you sip your morning brew, your adenosine receptors can’t tell the difference.

Specifically, caffeine attaches to the A1 receptor. With caffeine docked at the receptor, a lot of your body’s adenosine molecules can’t enter. It creates a traffic jam of sorts. With all that adenosine blocked, the caffeine keeps you from getting tired.

But that’s not where coffee’s kick comes from. With the adenosine receptor clogged, neurotransmitters like dopamine and glutamate can get a head start.

Your dopamine levels swell, giving you a mild jolt of energy. In a way, caffeine is like a bouncer. It blocks the door, keeping the tired molecules out while the more stimulating molecules party on.

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