South African captain AB de Villiers won the toss and decided to bat in the fourth day-night international against Pakistan at Sheikh Zayed Stadium on Friday.
South Africa remained unchanged from the side which won the third match in Abu Dhabi by 68 runs on Wedneday, taking a 2-1 lead in the five-match series.
They also won the first match in Sharjah by one run while Pakistan won the second match by 66 runs in Dubai.
Pakistan dropped out-of-form batsman Umar Amin and paceman Wahab Riaz to bring in Junaid Khan for his first match of the series and give a one-day debut to batsman Sohaib Maqsood.
Teams: Pakistan: Misbah-ul-Haq (capt), Ahmed Shehzad, Asad Shafiq, Junaid Khan, Mohammad Hafeez, Mohammad Irfan, Saeed Ajmal, Shahid Afridi, Sohaib Maqsood, Sohail Tanvir, Umar Akmal
South Africa: AB de Villiers (capt), Hashim Amla, Quinton de Kock, Jean-Paul Duminy, Faf du Plessis, Imran Tahir, Ryan McLaren, David Miller, Morne Morkel, Dale Steyn, Lonwabo Tsotsobe.
Umpires: Ahsan Raza (PAK) and Steve Davis (AUS) TV umpire: Richard Illingworth (ENG) Match referee: Ranjan Madugalle (SRI)