New technique spots how far cancer has spread

Researchers have developed a new technique that will allow surgeons to identify how far
the tumour has spread and help them decide which tissue to remove in order to save healthy cells in cancer patients. “With molecular-targeted imaging, surgeons can avoid
unnecessary removal of healthy lymph nodes which is better long-term for patients,” said Quyen T Nguyen, associate professor at University of California, San Diego School
of Medicine, The Indian Express reported here. “The range of the surgeon’s visual field is greatly enhanced by a molecular tool that can help achieve accurate surgical margins and detection of metastases so that no tumour is left behind,” Nguyen said.
Lymph nodes, located throughout the body, serve as filters that contain immune cells to fight infection and clean the blood. When cancer cells break away from a tumour,
the cells can travel through the lymph system and hide in these tiny organs.
Surgeons remove the nodes to determine if a cancer has spread. However, human nodes, only half a centimetre in size, are difficult to discern among the surrounding tissue during
Furthermore, even when surgeons are able to map the location of the nodes, there is no current technique that indicates whether or not the lymph nodes contain cancer,
requiring removal of more lymph nodes than necessary. “This research is significant because it shows real-time intra-operative detection of cancer metastases
in mice.